Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1128/AAC.01476-15 http://scihub22266oqcxt.onion/10.1128/AAC.01476-15 C4649170!4649170 !26349831     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26349831 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Antimicrob+Agents+Chemother 2015 ; 59 (12 ): 7786-9 Nephropedia Template TP {{tp|p=26349831 |t=2015. Eagle Effect in Nonreplicating Persister Mycobacteria |pdf=|usr=}}{{26349831 }} gab.com Text Eagle Effect in Nonreplicating Persister Mycobacteria JO: Antimicrob Agents Chemother http://www.kidney.de/pget.php?&tw=1&pmid=26349831 #FOAvip We determined the microbicidal activities of antibacterials against nonreplicating Mycobacterium smegmatis grown in a starvation-based Loebel model for persistence. Whereas most drugs lost their activity, fluoroquinolones retained lethal potency. Dose-response characterizations showed a paradoxical more-drug-kills-less Eagle effect. Pretreatment of cultures with chloramphenicol blocked the lethal action of the gyrase inhibitors. These results suggest that fluoroquinolones at low concentrations trigger a protein synthesis-dependent cell death pathway and shut off this suicide pathway at elevated concentrations. Twit Text FOAVip Eagle Effect in Nonreplicating Persister Mycobacteria ????Antimicrob Agents Chemother http://www.kidney.de/pget.php?&tw=1&pmid=26349831 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26349831 #FOAvip English Wikipedia <ref>{{Cite pmid|26349831 }}</ref> Eagle Effect in Nonreplicating Persister Mycobacteria #MMPMID26349831 Wu ML ; Tan J ; Dick T Antimicrob Agents Chemother 2015[Dec]; 59 (12 ): 7786-9 PMID26349831 show ga We determined the microbicidal activities of antibacterials against nonreplicating Mycobacterium smegmatis grown in a starvation-based Loebel model for persistence. Whereas most drugs lost their activity, fluoroquinolones retained lethal potency. Dose-response characterizations showed a paradoxical more-drug-kills-less Eagle effect. Pretreatment of cultures with chloramphenicol blocked the lethal action of the gyrase inhibitors. These results suggest that fluoroquinolones at low concentrations trigger a protein synthesis-dependent cell death pathway and shut off this suicide pathway at elevated concentrations. |Anti-Bacterial Agents/*pharmacology [MESH] |Chloramphenicol/pharmacology [MESH] |Culture Media [MESH] |DNA Gyrase [MESH] |Dose-Response Relationship, Drug [MESH] |Fluoroquinolones/pharmacology [MESH] |Microbial Sensitivity Tests [MESH] |Mycobacterium Infections, Nontuberculous/*microbiology [MESH] |Mycobacterium smegmatis/*drug effects/growth & development [MESH] |Protein Synthesis Inhibitors/pharmacology [MESH]Eagle Effect in Nonreplicating Persister Mycobacteria (epmc).pdf DeepDyve Pubget Overpricing