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2016 ; 17
(ä): 60
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EAGER: efficient ancient genome reconstruction
#MMPMID27036623
Peltzer A
; Jäger G
; Herbig A
; Seitz A
; Kniep C
; Krause J
; Nieselt K
Genome Biol
2016[Mar]; 17
(ä): 60
PMID27036623
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BACKGROUND: The automated reconstruction of genome sequences in ancient genome
analysis is a multifaceted process. RESULTS: Here we introduce EAGER, a
time-efficient pipeline, which greatly simplifies the analysis of large-scale
genomic data sets. EAGER provides features to preprocess, map, authenticate, and
assess the quality of ancient DNA samples. Additionally, EAGER comprises tools to
genotype samples to discover, filter, and analyze variants. CONCLUSIONS: EAGER
encompasses both state-of-the-art tools for each step as well as new
complementary tools tailored for ancient DNA data within a single integrated
solution in an easily accessible format.