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10.1186/s12964-015-0102-1 http://scihub22266oqcxt.onion/10.1186/s12964-015-0102-1 C4396812!4396812 !25889964     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25889964 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Cell+Commun+Signal 2015 ; 13 (ä): 24 Nephropedia Template TP {{tp|p=25889964 |t=2015. Dynasore - not just a dynamin inhibitor |pdf=|usr=}}{{25889964 }} gab.com Text Dynasore - not just a dynamin inhibitor JO: Cell Commun Signal http://www.kidney.de/pget.php?&tw=1&pmid=25889964 #FOAvip Dynamin is a GTPase protein that is essential for membrane fission during clathrin-mediated endocytosis in eukaryotic cells. Dynasore is a GTPase inhibitor that rapidly and reversibly inhibits dynamin activity, which prevents endocytosis. However, comparison between cells treated with dynasore and RNA interference of genes encoding dynamin, reveals evidence that dynasore reduces labile cholesterol in the plasma membrane, and disrupts lipid raft organization, in a dynamin-independent manner. To explore the role of dynamin it is important to use multiple dynamin inhibitors, alongside the use of dynamin mutants and RNA interference targeting genes encoding dynamin. On the other hand, dynasore provides an interesting tool to explore the regulation of cholesterol in plasma membranes. Twit Text FOAVip Dynasore - not just a dynamin inhibitor ????Cell Commun Signal http://www.kidney.de/pget.php?&tw=1&pmid=25889964 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25889964 #FOAvip English Wikipedia <ref>{{Cite pmid|25889964 }}</ref> Dynasore - not just a dynamin inhibitor #MMPMID25889964 Preta G ; Cronin JG ; Sheldon IM Cell Commun Signal 2015[Apr]; 13 (ä): 24 PMID25889964 show ga Dynamin is a GTPase protein that is essential for membrane fission during clathrin-mediated endocytosis in eukaryotic cells. Dynasore is a GTPase inhibitor that rapidly and reversibly inhibits dynamin activity, which prevents endocytosis. However, comparison between cells treated with dynasore and RNA interference of genes encoding dynamin, reveals evidence that dynasore reduces labile cholesterol in the plasma membrane, and disrupts lipid raft organization, in a dynamin-independent manner. To explore the role of dynamin it is important to use multiple dynamin inhibitors, alongside the use of dynamin mutants and RNA interference targeting genes encoding dynamin. On the other hand, dynasore provides an interesting tool to explore the regulation of cholesterol in plasma membranes. |Animals [MESH] |Cell Membrane/*metabolism [MESH] |Cholesterol/*metabolism [MESH] |Dynamins/*antagonists & inhibitors/metabolism [MESH] |Enzyme Inhibitors/*pharmacology [MESH] |Humans [MESH]Dynasore - not just a dynamin inhibitor (epmc).pdf DeepDyve Pubget Overpricing