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Drug vaping applied to cannabis: Is "Cannavaping" a therapeutic alternative to
marijuana?
#MMPMID27228348
Varlet V
; Concha-Lozano N
; Berthet A
; Plateel G
; Favrat B
; De Cesare M
; Lauer E
; Augsburger M
; Thomas A
; Giroud C
Sci Rep
2016[May]; 6
(?): 25599
PMID27228348
show ga
Therapeutic cannabis administration is increasingly used in Western countries due
to its positive role in several pathologies. Dronabinol or tetrahydrocannabinol
(THC) pills, ethanolic cannabis tinctures, oromucosal sprays or table vaporizing
devices are available but other cannabinoids forms can be used. Inspired by the
illegal practice of dabbing of butane hashish oil (BHO), cannabinoids from
cannabis were extracted with butane gas, and the resulting concentrate (BHO) was
atomized with specific vaporizing devices. The efficiency of "cannavaping,"
defined as the "vaping" of liquid refills for e-cigarettes enriched with
cannabinoids, including BHO, was studied as an alternative route of
administration for therapeutic cannabinoids. The results showed that illegal
cannavaping would be subjected to marginal development due to the poor solubility
of BHO in commercial liquid refills (especially those with high glycerin
content). This prevents the manufacture of liquid refills with high BHO
concentrations adopted by most recreational users of cannabis to feel the
psychoactive effects more rapidly and extensively. Conversely, "therapeutic
cannavaping" could be an efficient route for cannabinoids administration because
less concentrated cannabinoids-enriched liquid refills are required. However, the
electronic device marketed for therapeutic cannavaping should be carefully
designed to minimize potential overheating and contaminant generation.
|*Marijuana Smoking
[MESH]
|Butanes/administration & dosage/therapeutic use
[MESH]
|Cannabinoids/administration & dosage/therapeutic use
[MESH]
|Cannabis/*chemistry
[MESH]
|Dronabinol/administration & dosage/therapeutic use
[MESH]
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