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10.1097/MOH.0000000000000165 http://scihub22266oqcxt.onion/10.1097/MOH.0000000000000165 C4636909!4636909!26248003     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26248003.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Curr+Opin+Hematol 2015 ; 22 (5): 428-36 Nephropedia Template TP {{tp|p=26248003|t=2015. Dissecting the Genetic Determinants of Hemostasis and Thrombosis |pdf=|usr=}}{{26248003}} gab.com Text Dissecting the Genetic Determinants of Hemostasis and Thrombosis JO: Curr Opin Hematol http://www.kidney.de/pget.php?&tw=1&pmid=26248003 #FOAvip Purpose of Review: New DNA genotyping and sequencing technologies have facilitated the rapid advancement in our knowledge of human genomic variation and a search for the heritable determinants of complex genetic traits. This review highlights findings from recent genetic studies of complex traits primarily related to venous thromboembolism and provides tools to understand and interpret genome-wide association studies and next generation sequencing studies. Recent Findings: Genome-wide studies of venous thromboembolic disease and the variation of the protein components of the hemostatic system have been reported. The results of these studies have suggested that variants in a diverse set of known and new genes contribute to the heritability of these traits but that many of the genetic determinants of these traits still remain undiscovered. Summary: Next generation sequencing studies and functional studies of the gene loci that contribute to hemostatic traits are currently underway. Future studies that explore the role of rare genetic variants, regulatory elements of the genome and gene-gene interactions will be required for a more complete understanding of the genetic control of the hemostatic system and for the application of this knowledge to the care of patients with disorders of thrombosis and hemostasis. Twit Text FOAVip Dissecting the Genetic Determinants of Hemostasis and Thrombosis ????Curr Opin Hematol http://www.kidney.de/pget.php?&tw=1&pmid=26248003 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26248003 #FOAvip English Wikipedia <ref>{{Cite pmid|26248003}}</ref> Dissecting the Genetic Determinants of Hemostasis and Thrombosis #MMPMID26248003 Desch KC Curr Opin Hematol 2015[Sep]; 22 (5): 428-36 PMID26248003show ga Purpose of Review: New DNA genotyping and sequencing technologies have facilitated the rapid advancement in our knowledge of human genomic variation and a search for the heritable determinants of complex genetic traits. This review highlights findings from recent genetic studies of complex traits primarily related to venous thromboembolism and provides tools to understand and interpret genome-wide association studies and next generation sequencing studies. Recent Findings: Genome-wide studies of venous thromboembolic disease and the variation of the protein components of the hemostatic system have been reported. The results of these studies have suggested that variants in a diverse set of known and new genes contribute to the heritability of these traits but that many of the genetic determinants of these traits still remain undiscovered. Summary: Next generation sequencing studies and functional studies of the gene loci that contribute to hemostatic traits are currently underway. Future studies that explore the role of rare genetic variants, regulatory elements of the genome and gene-gene interactions will be required for a more complete understanding of the genetic control of the hemostatic system and for the application of this knowledge to the care of patients with disorders of thrombosis and hemostasis. äDissecting the Genetic Determinants of Hemostasis and Thrombosis (epmc).pdf DeepDyve Pubget Overpricing