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2020 ; 20
(7
): 392-394
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Dissecting antibody-mediated protection against SARS-CoV-2
#MMPMID32514035
Zohar T
; Alter G
Nat Rev Immunol
2020[Jul]; 20
(7
): 392-394
PMID32514035
show ga
Understanding the properties and mechanisms by which antibodies provide
protection is essential to defining immunity. Although neutralizing antibodies
have been proposed as a potential key mechanism of protection against many viral
pathogens, antibodies mediate additional immune functions that may have both
protective and pathological consequences. Dissecting these properties against
SARS-CoV-2 is likely necessary for defining metrics of immunity that will inform
the design of vaccines and therapeutics and improve clinical management.
|Animals
[MESH]
|Antibodies, Neutralizing/immunology
[MESH]
|Antibodies, Viral/blood/*immunology
[MESH]
|Antibody-Dependent Cell Cytotoxicity
[MESH]
|Antibody-Dependent Enhancement
[MESH]
|COVID-19
[MESH]
|COVID-19 Vaccines
[MESH]
|Coronavirus Infections/*immunology/prevention & control
[MESH]