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2016 ; 12
(ä): 2115-24
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Disruptive mood dysregulation disorder: current insights
#MMPMID27601906
Baweja R
; Mayes SD
; Hameed U
; Waxmonsky JG
Neuropsychiatr Dis Treat
2016[]; 12
(ä): 2115-24
PMID27601906
show ga
Disruptive mood dysregulation disorder (DMDD) was introduced as a new diagnostic
entity under the category of depressive disorders in Diagnostic and Statistical
Manual of Mental Disorders, Fifth Edition (DSM-5). It was included in DSM-5
primarily to address concerns about the misdiagnosis and consequent overtreatment
of bipolar disorder in children and adolescents. DMDD does provide a home for a
large percentage of referred children with severe persistent irritability that
did not fit well into any DSM, Fourth Edition (DSM-IV) diagnostic category.
However, it has been a controversial addition to the DSM-5 due to lack of
published validity studies, leading to questions about its validity as a distinct
disorder. In this article, the authors discuss the diagnostic criteria,
assessment, epidemiology, criticism of the diagnosis, and pathophysiology, as
well as treatment and future directions for DMDD. They also review the literature
on severe mood dysregulation, as described by the National Institute of Mental
Health, as the scientific support for DMDD is based primarily on studies of
severe mood dysregulation.
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