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2015 ; 37 Suppl 1
(0 1
): 85-91
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Disorders of erythrocyte volume homeostasis
#MMPMID25976965
Glogowska E
; Gallagher PG
Int J Lab Hematol
2015[May]; 37 Suppl 1
(0 1
): 85-91
PMID25976965
show ga
Inherited disorders of erythrocyte volume homeostasis are a heterogeneous group
of rare disorders with phenotypes ranging from dehydrated to overhydrated
erythrocytes. Clinical, laboratory, physiologic, and genetic heterogeneities
characterize this group of disorders. A series of recent reports have provided
novel insights into our understanding of the genetic bases underlying some of
these disorders of red cell volume regulation. This report reviews this progress
in understanding determinants that influence erythrocyte hydration and how they
have yielded a better understanding of the pathways that influence cellular water
and solute homeostasis.
|*Erythrocyte Volume
[MESH]
|*Homeostasis
[MESH]
|Anion Exchange Protein 1, Erythrocyte/genetics/metabolism
[MESH]
|Erythrocytes/*metabolism
[MESH]
|Glucose Transporter Type 1/genetics/metabolism
[MESH]