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10.1007/978-1-4939-7240-1_1 http://scihub22266oqcxt.onion/10.1007/978-1-4939-7240-1_1 C5931213!5931213 !28889281     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28889281 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28889281 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Methods+Mol+Biol 2017 ; 1657 (ä): 1-8 Nephropedia Template TP {{tp|p=28889281 |t=2017. Discovery of the Second Messenger Cyclic di-GMP |pdf=|usr=}}{{28889281 }} gab.com Text Discovery of the Second Messenger Cyclic di-GMP JO: Methods Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=28889281 #FOAvip The nearly ubiquitous bacterial second messenger cyclic di-GMP is involved in a multitude of fundamental physiological processes such as sessility/motility transition and the switch between the acute and chronic infection status, combined with cell cycle control. The discovery of cyclic di-GMP, though, has been an example par excellence of scientific serendipity. We recapitulate here its years-long discovery process as an activator of the cellulose synthase of the environmental bacterium Komagataeibacter xylinus and its consequences for follow-up research. Indeed, the discovery of cyclic di-GMP as a ubiquitous second messenger contributed to the change in perception of bacteria as simple unicellular organisms just randomly building-up multicellular communities. Subsequently, cyclic di-GMP also paved the way to the identification of other pro- and eukaryotic cyclic dinucleotide second messengers. Twit Text FOAVip Discovery of the Second Messenger Cyclic di-GMP ????Methods Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=28889281 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28889281 #FOAvip English Wikipedia <ref>{{Cite pmid|28889281 }}</ref> Discovery of the Second Messenger Cyclic di-GMP #MMPMID28889281 Römling U ; Galperin MY Methods Mol Biol 2017[]; 1657 (ä): 1-8 PMID28889281 show ga The nearly ubiquitous bacterial second messenger cyclic di-GMP is involved in a multitude of fundamental physiological processes such as sessility/motility transition and the switch between the acute and chronic infection status, combined with cell cycle control. The discovery of cyclic di-GMP, though, has been an example par excellence of scientific serendipity. We recapitulate here its years-long discovery process as an activator of the cellulose synthase of the environmental bacterium Komagataeibacter xylinus and its consequences for follow-up research. Indeed, the discovery of cyclic di-GMP as a ubiquitous second messenger contributed to the change in perception of bacteria as simple unicellular organisms just randomly building-up multicellular communities. Subsequently, cyclic di-GMP also paved the way to the identification of other pro- and eukaryotic cyclic dinucleotide second messengers. |*Research/history [MESH] |*Second Messenger Systems [MESH] |Bacteria/genetics/metabolism [MESH] |Bacterial Physiological Phenomena [MESH] |Biofilms [MESH] |Cyclic GMP/*analogs & derivatives/metabolism [MESH] |Eukaryotic Cells/metabolism [MESH] |Glucosyltransferases [MESH] |History, 20th Century [MESH]Discovery of the Second Messenger Cyclic di-GMP (epmc).pdf DeepDyve Pubget Overpricing