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10.1016/j.neulet.2025.138348 http://scihub22266oqcxt.onion/10.1016/j.neulet.2025.138348 40784612!ä!40784612 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=40784612&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\40784612.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Neurosci+Lett 2025 ; 865 (ä): 138348 Nephropedia Template TP {{tp|p=40784612|t=2025. Differential cholinergic modulation of parafascicular thalamic neurons |pdf=|usr=}}{{40784612}} gab.com Text Differential cholinergic modulation of parafascicular thalamic neurons JO: Neurosci Lett http://www.kidney.de/pget.php?&tw=1&pmid=40784612 #FOAvip The parafascicular (PF) thalamic nucleus participates in functions such as arousal, consciousness, learning, and behavioral flexibility, which are linked to its projections to the striatum and receives strong cholinergic input from the pedunculopontine nucleus. Using electrophysiological recordings, we identified two neuronal populations based on their afterhyperpolarization potential (AHP) characteristics: Brief AHP neurons and Prolonged AHP neurons. Only Prolonged AHP neurons were modulated by cholinergic receptor activation, which reduced AHP amplitude and duration, and increased their firing frequency. These effects were associated with SK-type calcium-activated potassium channels and specifically activated by M1 type muscarinic receptors. Together, these findings indicate clear differential cholinergic modulation in the PF thalamic nucleus, which may be related to its functional roles. Twit Text FOAVip Differential cholinergic modulation of parafascicular thalamic neurons ????Neurosci Lett http://www.kidney.de/pget.php?&tw=1&pmid=40784612 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=40784612 #FOAvip English Wikipedia <ref>{{Cite pmid|40784612}}</ref> Differential cholinergic modulation of parafascicular thalamic neurons #MMPMID40784612 Vazquez-Vazquez HA; Ortega A; Parrado Y; Laville A; Tapia D; Galarraga E Neurosci Lett 2025[Aug]; 865 (ä): 138348 PMID40784612show ga The parafascicular (PF) thalamic nucleus participates in functions such as arousal, consciousness, learning, and behavioral flexibility, which are linked to its projections to the striatum and receives strong cholinergic input from the pedunculopontine nucleus. Using electrophysiological recordings, we identified two neuronal populations based on their afterhyperpolarization potential (AHP) characteristics: Brief AHP neurons and Prolonged AHP neurons. Only Prolonged AHP neurons were modulated by cholinergic receptor activation, which reduced AHP amplitude and duration, and increased their firing frequency. These effects were associated with SK-type calcium-activated potassium channels and specifically activated by M1 type muscarinic receptors. Together, these findings indicate clear differential cholinergic modulation in the PF thalamic nucleus, which may be related to its functional roles. äDifferential cholinergic modulation of parafascicular thalamic neurons(epmc).pdf DeepDyve Pubget Overpricing