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2015 ; 3
(3
): 122-135
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Diagnosis of Helicobacter pylori: Changes towards the Future
#MMPMID28943614
Kalali B
; Formichella L
; Gerhard M
Diseases
2015[Jun]; 3
(3
): 122-135
PMID28943614
show ga
Since the first evidence demonstrating the dramatically high incidence of H.
pylori infection and the subsequent medical challenges it incurs, health
management of H. pylori infection has been a high priority for health authorities
worldwide. Despite a decreasing rate of infection in western countries,
prevalence of H. pylori infection in developing and in some industrial countries
is still very high. Whereas treatment and vaccination against H. pylori is a
contemporary issue in medical communities, selective treatment and prior
high-throughput screening of the subject population is a major concern of health
organizations. So far, diagnostic tests are either elaborative and require
relatively advanced medical care infrastructure or they do not fulfill the
criteria recommended by the Maastricht IV/Florence consensus report. In this
review, in light of recent scientific studies, we highlight current and possible
future approaches for the diagnosis of H. pylori. We point out that novel
non-invasive tests may not only cover the requirements of gold standard methods
in H. pylori detection but also offer the potential for risk stratification of
infection in a high throughput manner.