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2017 ; 32
(2
): 229-238
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Diagnosis and treatment of cystic lung disease
#MMPMID28264540
Park S
; Lee EJ
Korean J Intern Med
2017[Mar]; 32
(2
): 229-238
PMID28264540
show ga
Cystic lung disease (CLD) is a group of lung disorders characterized by the
presence of multiple cysts, defined as air-filled lucencies or low-attenuating
areas, bordered by a thin wall (usually < 2 mm). The recognition of CLDs has
increased with the widespread use of computed tomography. This article addresses
the mechanisms of cyst formation and the diagnostic approaches to CLDs. A number
of assessment methods that can be used to confirm CLDs are discussed, including
high-resolution computed tomography, pathologic approaches, and genetic/
serologic markers, together with treatment modalities, including new therapeutic
drugs currently being evaluated. The CLDs covered by this review are
lymphangioleiomyomatosis, pulmonary Langerhans cell histiocytosis, Birt-Hogg-Dube
syndrome, lymphocytic interstitial pneumonia/follicular bronchiolitis, and
amyloidosis.