Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28360465
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Diagnosis and management options in malignant pleural effusions
#MMPMID28360465
Dixit R
; Agarwal KC
; Gokhroo A
; Patil CB
; Meena M
; Shah NS
; Arora P
Lung India
2017[Mar]; 34
(2
): 160-166
PMID28360465
show ga
Malignant pleural effusion (MPE) denotes an advanced malignant disease process.
Most of the MPE are metastatic involvement of the pleura from primary malignancy
at lung, breast, and other body sites apart from lymphomas. The diagnosis of MPE
has been traditionally made on cytological examination of pleural fluid and/or
histological examination of pleural biopsy tissue that still remains the initial
approach in these cases. There has been tremendous advancement in the diagnosis
of MPE now a day with techniques i.e. characteristic Ultrasound and computed
tomography features, image guided biopsies, fluorodeoxyglucose-positron emission
tomography imaging, thoracoscopy with direct biopsy under vision, tumor marker
studies and immunocytochemical analysis etc., that have made possible an early
diagnosis of MPE. The management of MPE still remains a challenge to
pulmonologist and oncologist. Despite having various modalities with better
tolerance such as pleurodesis and indwelling pleural catheters etc., for
long-term control, all the management approaches remain palliative to improve the
quality of life and reduce symptoms. While choosing an appropriate management
intervention, one should consider the clinical status of the patient, life
expectancy, overall cost, availability and comparative institutional outcomes,
etc.