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2015 ; 4
(ä): 212281
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Diagnosis and management of lentigo maligna: a review
#MMPMID26082796
Kasprzak JM
; Xu YG
Drugs Context
2015[]; 4
(ä): 212281
PMID26082796
show ga
Lentigo maligna is a melanocytic neoplasm occurring on sun-exposed skin, usually
on the head and neck, of middle-aged and elderly patients. It is thought to
represent the in situ phase of lentigo maligna melanoma. The ill-defined nature
and potentially large size of lesions can pose significant diagnostic and
treatment challenges. The goal of therapy is to cure the lesions in order to
prevent development of invasive disease, and surgical excision is the treatment
of choice to achieve clear histological margins. Nonsurgical treatment modalities
have been reported; however, evidence is lacking to support their use. Age,
general health, and comorbidities need to be taken into account when deciding the
right treatment modality for each individual patient.