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10.1016/j.hoc.2013.02.001

http://scihub22266oqcxt.onion/10.1016/j.hoc.2013.02.001
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C3668315!3668315 !23714311
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suck abstract from ncbi


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pmid23714311
      Hematol+Oncol+Clin+North+Am 2013 ; 27 (3 ): 541-63
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  • Diagnosis and management of heparin-induced thrombocytopenia #MMPMID23714311
  • Lee GM ; Arepally GM
  • Hematol Oncol Clin North Am 2013[Jun]; 27 (3 ): 541-63 PMID23714311 show ga
  • Heparin-induced thrombocytopenia (HIT) is a prothrombotic disorder caused by antibodies to platelet factor 4/heparin (PF4/H) complexes. It presents with declining platelet counts 5 to 14 days after heparin administration and results in a predisposition to arterial and venous thrombosis. Establishing the diagnosis of HIT can be extremely challenging. It is essential to conduct a thorough clinical evaluation in addition to laboratory testing to confirm the presence of PF4/H antibodies. Multiple clinical algorithms have been developed to aid the clinician in predicting the likelihood of HIT. Once HIT is recognized, an alternative anticoagulant should be initiated to prevent further complications.
  • |Algorithms [MESH]
  • |Heparin/*adverse effects [MESH]
  • |Humans [MESH]


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