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10.7497/j.issn.2095-3941.2015.0020 http://scihub22266oqcxt.onion/10.7497/j.issn.2095-3941.2015.0020 C4607828!4607828!26487967     free     free     free Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26487967.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Cancer+Biol+Med 2015 ; 12 (3): 223-37 Nephropedia Template TP {{tp|p=26487967|t=2015. Development of targeted therapies in treatment of glioblastoma |pdf=|usr=}}{{26487967}} gab.com Text Development of targeted therapies in treatment of glioblastoma JO: Cancer Biol Med http://www.kidney.de/pget.php?&tw=1&pmid=26487967 #FOAvip Glioblastoma (GBM) is a type of tumor that is highly lethal despite maximal therapy. Standard therapeutic approaches provide modest improvement in progression-free and overall survival, necessitating the investigation of novel therapies. Oncologic therapy has recently experienced a rapid evolution toward ?targeted therapy?, with drugs directed against specific targets which play essential roles in the proliferation, survival, and invasiveness of GBM cells, including numerous molecules involved in signal transduction pathways. Inhibitors of these molecules have already entered or are undergoing clinical trials. However, significant challenges in their development remain because several preclinical and clinical studies present conflicting results. In this article, we will provide an up-to-date review of the current targeted therapies in GBM. Twit Text FOAVip Development of targeted therapies in treatment of glioblastoma ????Cancer Biol Med http://www.kidney.de/pget.php?&tw=1&pmid=26487967 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26487967 #FOAvip English Wikipedia <ref>{{Cite pmid|26487967}}</ref> Development of targeted therapies in treatment of glioblastoma #MMPMID26487967 Xu YY; Gao P; Sun Y; Duan YR Cancer Biol Med 2015[Sep]; 12 (3): 223-37 PMID26487967show ga Glioblastoma (GBM) is a type of tumor that is highly lethal despite maximal therapy. Standard therapeutic approaches provide modest improvement in progression-free and overall survival, necessitating the investigation of novel therapies. Oncologic therapy has recently experienced a rapid evolution toward ?targeted therapy?, with drugs directed against specific targets which play essential roles in the proliferation, survival, and invasiveness of GBM cells, including numerous molecules involved in signal transduction pathways. Inhibitors of these molecules have already entered or are undergoing clinical trials. However, significant challenges in their development remain because several preclinical and clinical studies present conflicting results. In this article, we will provide an up-to-date review of the current targeted therapies in GBM. äDevelopment of targeted therapies in treatment of glioblastoma (epmc).pdf DeepDyve Pubget Overpricing