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Usmanov DT
; Ninomiya S
; Chen LC
; Saha S
; Mandal MK
; Sakai Y
; Takaishi R
; Habib A
; Hiraoka K
; Yoshimura K
; Takeda S
; Wada H
; Nonami H
Mass Spectrom (Tokyo)
2017[]; 6
(Spec Iss
): S0059
PMID28337398
show ga
In mass spectrometry, analytes must be released in the gas phase. There are two
representative methods for the gasification of the condensed samples, i.e.,
ablation and desorption. While ablation is based on the explosion induced by the
energy accumulated in the condensed matrix, desorption is a single molecular
process taking place on the surface. In this paper, desorption methods for mass
spectrometry developed in our laboratory: flash heating/rapid cooling,
Leidenfrost phenomenon-assisted thermal desorption (LPTD), solid/solid friction,
liquid/solid friction, electrospray droplet impact (EDI) ionization/desorption,
and probe electrospray ionization (PESI), will be described. All the methods are
concerned with the surface and interface phenomena. The concept of how to desorb
less-volatility compounds from the surface will be discussed.