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10.1080/21541248.2016.1173767 http://scihub22266oqcxt.onion/10.1080/21541248.2016.1173767 C5003542!5003542 !27104658     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27104658 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27104658 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Small+GTPases 2016 ; 7 (3 ): 123-38 Nephropedia Template TP {{tp|p=27104658 |t=2016. Deregulation of Rho GTPases in cancer |pdf=|usr=}}{{27104658 }} gab.com Text Deregulation of Rho GTPases in cancer JO: Small GTPases http://www.kidney.de/pget.php?&tw=1&pmid=27104658 #FOAvip In vitro and in vivo studies and evidence from human tumors have long implicated Rho GTPase signaling in the formation and dissemination of a range of cancers. Recently next generation sequencing has identified direct mutations of Rho GTPases in human cancers. Moreover, the effects of ablating genes encoding Rho GTPases and their regulators in mouse models, or through pharmacological inhibition, strongly suggests that targeting Rho GTPase signaling could constitute an effective treatment. In this review we will explore the various ways in which Rho signaling can be deregulated in human cancers. Twit Text FOAVip Deregulation of Rho GTPases in cancer ????Small GTPases http://www.kidney.de/pget.php?&tw=1&pmid=27104658 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27104658 #FOAvip English Wikipedia <ref>{{Cite pmid|27104658 }}</ref> Deregulation of Rho GTPases in cancer #MMPMID27104658 Porter AP ; Papaioannou A ; Malliri A Small GTPases 2016[Jul]; 7 (3 ): 123-38 PMID27104658 show ga In vitro and in vivo studies and evidence from human tumors have long implicated Rho GTPase signaling in the formation and dissemination of a range of cancers. Recently next generation sequencing has identified direct mutations of Rho GTPases in human cancers. Moreover, the effects of ablating genes encoding Rho GTPases and their regulators in mouse models, or through pharmacological inhibition, strongly suggests that targeting Rho GTPase signaling could constitute an effective treatment. In this review we will explore the various ways in which Rho signaling can be deregulated in human cancers. |Animals [MESH] |DNA Copy Number Variations [MESH] |Enzyme Inhibitors/pharmacology/therapeutic use [MESH] |Gene Expression Regulation, Neoplastic/drug effects [MESH] |Humans [MESH] |Mutation [MESH] |Neoplasms/drug therapy/*enzymology/genetics [MESH]Deregulation of Rho GTPases in cancer (epmc).pdf DeepDyve Pubget Overpricing