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10.1097/ACI.0000000000000322 http://scihub22266oqcxt.onion/10.1097/ACI.0000000000000322 C5087571!5087571 !27755182     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27755182 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27755182 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Curr+Opin+Allergy+Clin+Immunol 2016 ; 16 (6 ): 530-540 Nephropedia Template TP {{tp|p=27755182 |t=2016. Dendritic cell analysis in primary immunodeficiency |pdf=|usr=}}{{27755182 }} gab.com Text Dendritic cell analysis in primary immunodeficiency JO: Curr Opin Allergy Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=27755182 #FOAvip PURPOSE OF REVIEW: Dendritic cells are specialized antigen-presenting cells which link innate and adaptive immunity, through recognition and presentation of antigen to T cells. Although the importance of dendritic cells has been demonstrated in many animal models, their contribution to human immunity remains relatively unexplored in vivo.Given their central role in infection, autoimmunity, and malignancy, dendritic cell deficiency or dysfunction would be expected to have clinical consequences. RECENT FINDINGS: Human dendritic cell deficiency disorders, related to GATA binding protein 2 (GATA2) and interferon regulatory factor 8 (IRF8) mutations, have highlighted the importance of dendritic cells and monocytes in primary immunodeficiency diseases and begun to shed light on their nonredundant roles in host defense and immune regulation in vivo. The contribution of dendritic cell and monocyte dysfunction to the pathogenesis of primary immunodeficiency disease phenotypes is becoming increasingly apparent. However, dendritic cell analysis is not yet a routine part of primary immunodeficiency disease workup. SUMMARY: Widespread uptake of dendritic cell/monocyte screening in clinical practice will facilitate the discovery of novel dendritic cell and monocyte disorders as well as advancing our understanding of human dendritic cell biology in health and disease. Twit Text FOAVip Dendritic cell analysis in primary immunodeficiency ????Curr Opin Allergy Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=27755182 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27755182 #FOAvip English Wikipedia <ref>{{Cite pmid|27755182 }}</ref> Dendritic cell analysis in primary immunodeficiency #MMPMID27755182 Bigley V ; Barge D ; Collin M Curr Opin Allergy Clin Immunol 2016[Dec]; 16 (6 ): 530-540 PMID27755182 show ga PURPOSE OF REVIEW: Dendritic cells are specialized antigen-presenting cells which link innate and adaptive immunity, through recognition and presentation of antigen to T cells. Although the importance of dendritic cells has been demonstrated in many animal models, their contribution to human immunity remains relatively unexplored in vivo.Given their central role in infection, autoimmunity, and malignancy, dendritic cell deficiency or dysfunction would be expected to have clinical consequences. RECENT FINDINGS: Human dendritic cell deficiency disorders, related to GATA binding protein 2 (GATA2) and interferon regulatory factor 8 (IRF8) mutations, have highlighted the importance of dendritic cells and monocytes in primary immunodeficiency diseases and begun to shed light on their nonredundant roles in host defense and immune regulation in vivo. The contribution of dendritic cell and monocyte dysfunction to the pathogenesis of primary immunodeficiency disease phenotypes is becoming increasingly apparent. However, dendritic cell analysis is not yet a routine part of primary immunodeficiency disease workup. SUMMARY: Widespread uptake of dendritic cell/monocyte screening in clinical practice will facilitate the discovery of novel dendritic cell and monocyte disorders as well as advancing our understanding of human dendritic cell biology in health and disease. |Adaptive Immunity [MESH] |Animals [MESH] |Antigen Presentation [MESH] |Autoimmunity [MESH] |Dendritic Cells/*physiology [MESH] |GATA2 Transcription Factor/*genetics [MESH] |Humans [MESH] |Immunologic Deficiency Syndromes/genetics/*immunology [MESH] |Interferon Regulatory Factors/*genetics [MESH] |Monocytes/*physiology [MESH] |Mutation/genetics [MESH]Dendritic cell analysis in primary immunodeficiency (epmc).pdf DeepDyve Pubget Overpricing