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2017 ; 29
(2
): 215-218
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Degos-Like Lesions Associated with Systemic Lupus Erythematosus
#MMPMID28392651
Jang MS
; Park JB
; Yang MH
; Jang JY
; Kim JH
; Lee KH
; Kim GT
; Hwangbo H
; Suh KS
Ann Dermatol
2017[Apr]; 29
(2
): 215-218
PMID28392651
show ga
Degos disease, also referred to as malignant atrophic papulosis, was first
described in 1941 by Köhlmeier and was independently described by Degos in 1942.
Degos disease is characterized by diffuse, papular skin eruptions with
porcelain-white centers and slightly raised erythematous telangiectatic rims
associated with bowel infarction. Although the etiology of Degos disease is
unknown, autoimmune diseases, coagulation disorders, and vasculitis have all been
considered as underlying pathogenic mechanisms. Approximately 15% of Degos
disease have a benign course limited to the skin and no history of
gastrointestinal or central nervous system (CNS) involvement. A 29-year-old
female with history of systemic lupus erythematosus (SLE) presented with a 2-year
history of asymptomatic lesions on the dorsum of all fingers and both knees. The
patient had only skin lesions and no gastrointestinal or CNS vasculitis symptoms.
Her skin lesions were umbilicated, atrophic porcelain-white lesions with a rim of
erythema. On the basis of clinical, histologic, and laboratory findings, a
diagnosis of Degos-like lesions associated with SLE was made. The patient had
been treated for SLE for 7 years. Her treatment regimen was maintained over a 2
month follow-up period, and the skin lesions improved slightly with no
development of new lesions.