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2015 ; 48
(1
): 1-6
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Definition of critical asthma syndromes
#MMPMID24213844
Kenyon N
; Zeki AA
; Albertson TE
; Louie S
Clin Rev Allergy Immunol
2015[Feb]; 48
(1
): 1-6
PMID24213844
show ga
Urgent visits to the clinic and emergency department for acute severe asthma
exacerbations are all too frequent. Existing national guidelines do not present
consistent or specific recommendations for the evaluation and treatment of
individual asthma patients in respiratory distress. In this vein, we propose the
term "critical asthma syndrome" (CAS) to describe any child or adult who is at
high risk for fatal asthma. Acute severe asthma, refractory asthma, status
asthmaticus, and near-fatal asthma all describe CAS where physical exhaustion
from the overwhelming work of breathing leads to respiratory arrest and death
from hypoxia or related complications. The authors of this supplement seek to
emphasize the importance of early recognition, prompt and coordinated evaluation,
and treatment of CAS in the emergency department, hospital, and intensive care
units by experienced healthcare provider teams. CAS is not severe persistent
asthma where control of symptoms and prevention of exacerbations are targets of
chronic disease management in the outpatient setting. The authors address the
distinctions between the two entities throughout the supplement, and elaborate on
the considerations important in the care of a critically ill patient, including
the common errors to avoid. In addition, gaps in knowledge and clinical
experience in regards to critical asthma are highlighted. Knowledge gaps include
a lack of understanding of how to recognize CAS, how to coordinate and integrate
hospital and outpatient resources, when to further phenotype patients with
critical asthma in order to facilitate effective treatment, and how to prevent
future acute exacerbations. Lastly, CAS is complicated by the fact that asthma
care in diverse healthcare settings is haphazard. We recommend that primary care
physicians refer patients promptly to an asthma specialist for consultation to
reduce the frequency of acute exacerbations and prevent the development of CAS.