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2017 ; 13
(1
): 89-98
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Decision Support System for Lymphoma Classification
#MMPMID28491014
Negm AE
; Kandil AH
; Hassan OAE
Curr Med Imaging Rev
2017[Feb]; 13
(1
): 89-98
PMID28491014
show ga
The diffuse lymphoma is a malignant tumor of lymphoid tissues. It is associated
with abnormal, unlimited and uncontrolled proliferation of lymphoid cells. Until
now, expert pathologists have identified diffuse lymphoma cells disease manually.
This paper introduces automatic system with a friendly user interface to
differentiate between the categories of the diffuse lymphoma cells. This research
is based on the morphological features such as size, perimeter and circularity.
The cell size is a critical element in the classification of diffuse lymphoma
according to international formulation standards. Therefore, the applied
procedures identify lymphoid cell population in digital microscopic images. The
cells are classified using their morphological data according to the
characteristics of each cell such as: circularity, perimeter, area, and color
density. The number of cells is taken into consideration in the developed
approach. Image processing techniques are applied to digital microscopic images
to measure morphological parameters and to overcome image problems such as
overlapping and cell distortion that affect the sensitivity of the measured data.
The developed procedures help the pathologists to come to a decision regarding
the classification of diffuse lymphoma. Moreover, it can be used to train medical
students and young pathologists.
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