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2015 ; 22
(1
): 9
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Data integration in biological research: an overview
#MMPMID26336651
Lapatas V
; Stefanidakis M
; Jimenez RC
; Via A
; Schneider MV
J Biol Res (Thessalon)
2015[Dec]; 22
(1
): 9
PMID26336651
show ga
Data sharing, integration and annotation are essential to ensure the
reproducibility of the analysis and interpretation of the experimental findings.
Often these activities are perceived as a role that bioinformaticians and
computer scientists have to take with no or little input from the experimental
biologist. On the contrary, biological researchers, being the producers and often
the end users of such data, have a big role in enabling biological data
integration. The quality and usefulness of data integration depend on the
existence and adoption of standards, shared formats, and mechanisms that are
suitable for biological researchers to submit and annotate the data, so it can be
easily searchable, conveniently linked and consequently used for further
biological analysis and discovery. Here, we provide background on what is data
integration from a computational science point of view, how it has been applied
to biological research, which key aspects contributed to its success and future
directions.