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10.1038/cr.2015.13

http://scihub22266oqcxt.onion/10.1038/cr.2015.13
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C4349248!4349248 !25633593
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suck abstract from ncbi


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pmid25633593
      Cell+Res 2015 ; 25 (3 ): 273-4
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  • DUBA-UBR5 axis: other than transactivation #MMPMID25633593
  • Wu C ; Chen Z ; Kuchroo VK
  • Cell Res 2015[Mar]; 25 (3 ): 273-4 PMID25633593 show ga
  • The genomic and transcriptomic analysis has led to the identification of transcriptional networks that affect the differentiation of Th17 cells, while the protein-protein networks and the posttranslational modifications that control the development of Th17 cells have not been established yet. A recent publication by Rutz et al. in Nature describes a novel deubiquitylating enzyme DUBA as a negative regulator for IL-17 by regulating stability of ROR?t, the master transcription factor that induces Th17 cells.
  • |*Protein Biosynthesis [MESH]
  • |Animals [MESH]
  • |Female [MESH]
  • |Interleukin-17/*biosynthesis [MESH]
  • |Th17 Cells/*metabolism [MESH]


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