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2016 ; 61
(6
): 668-671
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Cutaneous Manifestations of Multiple Myeloma
#MMPMID27904188
Behera B
; Pattnaik M
; Sahu B
; Mohanty P
; Jena S
; Mohapatra L
Indian J Dermatol
2016[Nov]; 61
(6
): 668-671
PMID27904188
show ga
Multiple myeloma (MM) is a proliferative disorder of plasma cells which produce
abnormal immunoglobulin proteins. Skin involvement is rarely found in this
disorder. They are either specific or nonspecific lesions. We report four such
interesting patients who presented to us initially with common dermatoses such as
leukocytoclastic vasculitis, pyoderma gangrenosum, and vesiculobullous disorders
and were subsequently diagnosed to have MM. There were no skeletal involvements
or renal function abnormality at the time of presentation. Unusual presentation,
nonresponsiveness to conventional therapy, and abnormal blood parameters prompted
us to suspect some underlying systemic conditions which were later confirmed to
be MM after serum immunoelectrophoresis for M-band and bone marrow biopsy.