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2015 ; 48
(ä): 651-62
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Current wound healing procedures and potential care
#MMPMID25579968
Dreifke MB
; Jayasuriya AA
; Jayasuriya AC
Mater Sci Eng C Mater Biol Appl
2015[Mar]; 48
(ä): 651-62
PMID25579968
show ga
In this review, we describe current and future potential wound healing treatments
for acute and chronic wounds. The current wound healing approaches are based on
autografts, allografts, and cultured epithelial autografts, and wound dressings
based on biocompatible and biodegradable polymers. The Food and Drug
Administration approved wound healing dressings based on several polymers
including collagen, silicon, chitosan, and hyaluronic acid. The new potential
therapeutic intervention for wound healing includes sustained delivery of growth
factors, and siRNA delivery, targeting microRNA, and stem cell therapy. In
addition, environment sensors can also potentially utilize to monitor and manage
microenvironment at wound site. Sensors use optical, odor, pH, and hydration
sensors to detect such characteristics as uric acid level, pH, protease level,
and infection - all in the hopes of early detection of complications.
|*Biological Dressings
[MESH]
|*Wound Healing
[MESH]
|Acute Disease
[MESH]
|Cell- and Tissue-Based Therapy/*methods
[MESH]
|Cellular Microenvironment
[MESH]
|Chitosan/therapeutic use
[MESH]
|Chronic Disease
[MESH]
|Collagen/therapeutic use
[MESH]
|Humans
[MESH]
|Hyaluronic Acid/therapeutic use
[MESH]
|Intercellular Signaling Peptides and Proteins/therapeutic use
[MESH]