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English Wikipedia
Current strategies to treat tuberculosis
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Podany AT
; Swindells S
F1000Res
2016[]; 5
(ä): ä PMID27853505
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Tuberculosis (TB) has been a leading cause of death for more than a century.
While effective therapies exist, treatment is long and cumbersome. TB control is
complicated by the overlapping problems created by global inadequacy of public
health infrastructures, the interaction of the TB and human immunodeficiency
virus (HIV) epidemics, and the emergence of drug-resistant TB. After a long
period of neglect, there is now significant progress in the development of novel
treatment regimens for TB. Focusing on treatment for active disease, we review
pathways to TB regimen development and the new and repurposed anti-TB agents in
clinical development.