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10.1039/c6cs00803h

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suck abstract from ncbi


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pmid28393954
      Chem+Soc+Rev 2017 ; 46 (8 ): 2038-2056
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  • Current detection technologies for circulating tumor cells #MMPMID28393954
  • Shen Z ; Wu A ; Chen X
  • Chem Soc Rev 2017[Apr]; 46 (8 ): 2038-2056 PMID28393954 show ga
  • Circulating tumor cells (CTCs) are cancer cells that circulate in the blood stream after being naturally shed from original or metastatic tumors, and can lead to a new fatal metastasis. CTCs have become a hotspot research field during the last decade. Detection of CTCs, as a liquid biopsy of tumors, can be used for early diagnosis of cancers, earlier evaluation of cancer recurrence and chemotherapeutic efficacy, and choice of individual sensitive anti-cancer drugs. Therefore, CTC detection is a crucial tool to fight against cancer. Herein, we classify the currently reported CTC detection technologies, introduce some representative samples for each technology, conclude the advantages and limitations, and give a future perspective including the challenges and opportunities of CTC detection.
  • |*Neoplastic Cells, Circulating [MESH]
  • |Animals [MESH]
  • |Blood Circulation [MESH]
  • |Humans [MESH]
  • |Lignans [MESH]
  • |Limit of Detection [MESH]
  • |Nanostructures/*chemistry [MESH]
  • |Neoplasms/*diagnosis/*metabolism [MESH]
  • |Optical Imaging/methods [MESH]
  • |Particle Size [MESH]
  • |Spectrum Analysis/methods [MESH]


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