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2014 ; 2014
(ä): 708574
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Current Options for Determining Fracture Union
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Morshed S
Adv Med
2014[]; 2014
(ä): 708574
PMID26556422
show ga
Determining whether a bone fracture is healed is one of the most important and
fundamental clinical determinations made in orthopaedics. However, there are
currently no standardized methods of assessing fracture union, which in turn has
created significant disagreement among orthopaedic surgeons in both clinical and
research settings. An extensive amount of research has been dedicated to finding
novel and reliable ways of determining healing with some promising results.
Recent advancements in imaging techniques and introduction of new radiographic
scores have helped decrease the amount of disagreement on this topic among
physicians. The knowledge gained from biomechanical studies of bone healing has
helped us refine our tools and create more efficient and practical research
instruments. Additionally, a deeper understanding of the molecular pathways
involved in the bone healing process has led to emergence of serologic markers as
possible candidates in assessment of fracture union. In addition to our current
physician centered methods, patient-centered approaches assessing quality of life
and function are gaining popularity in assessment of fracture union. Despite
these advances, assessment of union remains an imperfect practice in the clinical
setting. Therefore, clinicians need to draw on multiple modalities that directly
and indirectly measure or correlate with bone healing when counseling patients.
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