Current Challenges in the Management of Prolactinomas
#MMPMID29632566
Maiter D
Eur Endocrinol
2015[Apr]; 11
(1
): 39-40
PMID29632566
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Although the diagnosis of prolactinoma is often straightforward and the treatment
strategy has been well defined in recent guidelines, several challenging issues
persist in their management. The differential diagnosis of a large pituitary
tumour with moderately elevated prolactin (PRL) concentrations is sometimes
difficult, and prolonged treatment with a dopamine agonist may be inappropriate
when the diagnosis of a prolactinoma is not sufficiently well substantiated.
Also, timely withdrawal of dopamine agonist treatment and the remaining
indications of transsphenoidal surgery are still matters of debate. Last but not
least, the management of resistant or aggressive prolactinomas remains a
challenge for the clinician, especially when they occur in young patients.
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