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10.1007/s00018-008-7452-4 http://scihub22266oqcxt.onion/10.1007/s00018-008-7452-4 C4686230!4686230 !18324353     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\18324353 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Cell+Mol+Life+Sci 2008 ; 65 (11 ): 1631-52 Nephropedia Template TP {{tp|p=18324353 |t=2008. Curcumin: from ancient medicine to current clinical trials |pdf=|usr=}}{{18324353 }} gab.com Text Curcumin: from ancient medicine to current clinical trials JO: Cell Mol Life Sci http://www.kidney.de/pget.php?&tw=1&pmid=18324353 #FOAvip Curcumin is the active ingredient in the traditional herbal remedy and dietary spice turmeric (Curcuma longa). Curcumin has a surprisingly wide range of beneficial properties, including anti-inflammatory, antioxidant, chemopreventive and chemotherapeutic activity. The pleiotropic activities of curcumin derive from its complex chemistry as well as its ability to influence multiple signaling pathways, including survival pathways such as those regulated by NF-kappaB, Akt, and growth factors; cytoprotective pathways dependent on Nrf2; and metastatic and angiogenic pathways. Curcumin is a free radical scavenger and hydrogen donor, and exhibits both pro- and antioxidant activity. It also binds metals, particularly iron and copper, and can function as an iron chelator. Curcumin is remarkably non-toxic and exhibits limited bioavailability. Curcumin exhibits great promise as a therapeutic agent, and is currently in human clinical trials for a variety of conditions, including multiple myeloma, pancreatic cancer, myelodysplastic syndromes, colon cancer, psoriasis and Alzheimer's disease. Twit Text FOAVip Curcumin: from ancient medicine to current clinical trials ????Cell Mol Life Sci http://www.kidney.de/pget.php?&tw=1&pmid=18324353 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=18324353 #FOAvip English Wikipedia <ref>{{Cite pmid|18324353 }}</ref> Curcumin: from ancient medicine to current clinical trials #MMPMID18324353 Hatcher H ; Planalp R ; Cho J ; Torti FM ; Torti SV Cell Mol Life Sci 2008[Jun]; 65 (11 ): 1631-52 PMID18324353 show ga Curcumin is the active ingredient in the traditional herbal remedy and dietary spice turmeric (Curcuma longa). Curcumin has a surprisingly wide range of beneficial properties, including anti-inflammatory, antioxidant, chemopreventive and chemotherapeutic activity. The pleiotropic activities of curcumin derive from its complex chemistry as well as its ability to influence multiple signaling pathways, including survival pathways such as those regulated by NF-kappaB, Akt, and growth factors; cytoprotective pathways dependent on Nrf2; and metastatic and angiogenic pathways. Curcumin is a free radical scavenger and hydrogen donor, and exhibits both pro- and antioxidant activity. It also binds metals, particularly iron and copper, and can function as an iron chelator. Curcumin is remarkably non-toxic and exhibits limited bioavailability. Curcumin exhibits great promise as a therapeutic agent, and is currently in human clinical trials for a variety of conditions, including multiple myeloma, pancreatic cancer, myelodysplastic syndromes, colon cancer, psoriasis and Alzheimer's disease. |*Anti-Inflammatory Agents, Non-Steroidal/chemistry/metabolism/therapeutic use [MESH] |*Antineoplastic Agents/chemistry/metabolism/therapeutic use [MESH] |*Antioxidants/chemistry/metabolism/therapeutic use [MESH] |*Curcumin/chemistry/metabolism/therapeutic use [MESH] |*Free Radical Scavengers/chemistry/metabolism/therapeutic use [MESH] |Clinical Trials as Topic [MESH] |Curcuma/chemistry [MESH] |Humans [MESH] |Iron/metabolism [MESH] |NF-kappa B/antagonists & inhibitors [MESH] |Neoplasms/drug therapy/pathology [MESH] |Oxidation-Reduction [MESH]Curcumin: from ancient medicine to current clinical trials (epmc).pdf DeepDyve Pubget Overpricing