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10.1097/MNH.0000000000000117 http://scihub22266oqcxt.onion/10.1097/MNH.0000000000000117 C4465999!4465999 !25887901     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25887901 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25887901 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Curr+Opin+Nephrol+Hypertens 2015 ; 24 (3 ): 231-8 Nephropedia Template TP {{tp|p=25887901 |t=2015. Crosstalk in glomerular injury and repair |pdf=|usr=}}{{25887901 }} gab.com Text Crosstalk in glomerular injury and repair JO: Curr Opin Nephrol Hypertens http://www.kidney.de/pget.php?&tw=1&pmid=25887901 #FOAvip PURPOSE OF REVIEW: The glomerulus is a unique structure required for filtration of blood, while retaining plasma proteins based on size and charge selectivity. Distinct cell types form the structural unit that creates the filtration barrier. Structurally, fenestrated endothelial cells line the capillary loops and lie in close contact with mesangial cells. Podocytes are connected by specialized intercellular junctions known as slit diaphragms and separated from the endothelial compartment by the glomerular basement membrane. In order for this highly specialized structure to function, cross-communication between these cells must occur. RECENT FINDINGS: Although classical studies have established key roles for vascular endothelial and platelet-derived growth factors in glomerular cross-communication, novel paracrine signaling pathways within the glomerulus have recently been identified. In addition, unique cellular pathways of established signaling cascades have been identified that are important for maintaining glomerular barrier function in health and disease. SUMMARY: Here, we will review our current understanding of the processes of cross-communication between the unique cellular constituents forming the glomerular filtration unit. We will highlight recent findings of cellular crosstalk via signaling pathways that regulate glomerular barrier function in pathophysiological conditions. Twit Text FOAVip Crosstalk in glomerular injury and repair ????Curr Opin Nephrol Hypertens http://www.kidney.de/pget.php?&tw=1&pmid=25887901 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25887901 #FOAvip English Wikipedia <ref>{{Cite pmid|25887901 }}</ref> Crosstalk in glomerular injury and repair #MMPMID25887901 Dimke H ; Maezawa Y ; Quaggin SE Curr Opin Nephrol Hypertens 2015[May]; 24 (3 ): 231-8 PMID25887901 show ga PURPOSE OF REVIEW: The glomerulus is a unique structure required for filtration of blood, while retaining plasma proteins based on size and charge selectivity. Distinct cell types form the structural unit that creates the filtration barrier. Structurally, fenestrated endothelial cells line the capillary loops and lie in close contact with mesangial cells. Podocytes are connected by specialized intercellular junctions known as slit diaphragms and separated from the endothelial compartment by the glomerular basement membrane. In order for this highly specialized structure to function, cross-communication between these cells must occur. RECENT FINDINGS: Although classical studies have established key roles for vascular endothelial and platelet-derived growth factors in glomerular cross-communication, novel paracrine signaling pathways within the glomerulus have recently been identified. In addition, unique cellular pathways of established signaling cascades have been identified that are important for maintaining glomerular barrier function in health and disease. SUMMARY: Here, we will review our current understanding of the processes of cross-communication between the unique cellular constituents forming the glomerular filtration unit. We will highlight recent findings of cellular crosstalk via signaling pathways that regulate glomerular barrier function in pathophysiological conditions. |Animals [MESH] |Capillaries/metabolism [MESH] |Endothelial Cells/*metabolism [MESH] |Humans [MESH] |Kidney Diseases/metabolism/*therapy [MESH] |Kidney Glomerulus/*injuries/*metabolism [MESH] |Mesangial Cells/*metabolism [MESH]Crosstalk in glomerular injury and repair (epmc).pdf DeepDyve Pubget Overpricing