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2015 ; 6
(4
): 301-9
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Crosstalk between mitochondria and peroxisomes
#MMPMID26629313
Demarquoy J
; Le Borgne F
World J Biol Chem
2015[Nov]; 6
(4
): 301-9
PMID26629313
show ga
Mitochondria and peroxisomes are small ubiquitous organelles. They both play
major roles in cell metabolism, especially in terms of fatty acid metabolism,
reactive oxygen species (ROS) production, and ROS scavenging, and it is now clear
that they metabolically interact with each other. These two organelles share some
properties, such as great plasticity and high potency to adapt their form and
number according to cell requirements. Their functions are connected, and any
alteration in the function of mitochondria may induce changes in peroxisomal
physiology. The objective of this paper was to highlight the interconnection and
the crosstalk existing between mitochondria and peroxisomes. Special emphasis was
placed on the best known connections between these organelles: origin, structure,
and metabolic interconnections.