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2018 ; 15
(6
): 8447-8453
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Cronkhite-Canada syndrome: A case report
#MMPMID29805581
Yuan W
; Tian L
; Ai FY
; Liu SJ
; Shen SR
; Wang XY
; Liu F
Oncol Lett
2018[Jun]; 15
(6
): 8447-8453
PMID29805581
show ga
Cronkhite-Canada syndrome (CCS) is a rare non-inherited condition characterized
by gastrointestinal (GI) hamartomatous polyposis, alopecia, onychodystrophy,
hyperpigmentation, weight loss and diarrhea. The etiology is most likely
autoimmune and diagnosis is based on patient history, physical examination,
endoscopic findings of GI polyposis and histology. The disease is very rare; thus
far more than 500 cases of CCS have been reported globally. A 58-years-old male
with CCS was reported in the present case study. The patient experienced a
history of diarrhea and hematochezia for 4 months, with abdominal pain for 1
month and additional nail and toenail loss for half a month. The clinical,
endoscopic and histological data confirmed the diagnosis.