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10.1002/dvg.20396 http://scihub22266oqcxt.onion/10.1002/dvg.20396 C4539156!4539156 !18543320     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=18543320 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\18543320 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Genesis 2008 ; 46 (6 ): 300-7 Nephropedia Template TP {{tp|p=18543320 |t=2008. Cre-mediated recombination in mouse Clara cells |pdf=|usr=}}{{18543320 }} gab.com Text Cre-mediated recombination in mouse Clara cells JO: Genesis http://www.kidney.de/pget.php?&tw=1&pmid=18543320 #FOAvip Clara cells are nonciliated secretory cells lining the respiratory epithelium and are easily identified by the expression of Clara cell secretory protein (CCSP). To investigate molecular mechanism(s) regulating Clara cell function in the lungs, Cre recombinase was inserted into exon 1 of the CCSP, generating two novel mouse models, CCSP(Cre-Neo) and CCSP(Cre). These two models differ only by the inclusion of the neomycin resistance gene. These mice were bred to the R26R reporter mouse to investigate the tissue and cell specificity of Cre-mediated recombination. The efficiency of Cre recombination in the CCSP(Cre) mouse model was higher than in the CCSP(Cre-Neo) mouse model. Recombination was detected at D 4.5 in CCSP(Cre-Neo)/R26R mice and at D 0.5 in CCSP(Cre)/R26R mice. The CCSP(Cre-Neo) and CCSP(Cre) mouse models provide valuable tools for the ablation of genes in the postnatal mouse Clara cells. Twit Text FOAVip Cre-mediated recombination in mouse Clara cells ????Genesis http://www.kidney.de/pget.php?&tw=1&pmid=18543320 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=18543320 #FOAvip English Wikipedia <ref>{{Cite pmid|18543320 }}</ref> Cre-mediated recombination in mouse Clara cells #MMPMID18543320 Li H ; Cho SN ; Evans CM ; Dickey BF ; Jeong JW ; DeMayo FJ Genesis 2008[Jun]; 46 (6 ): 300-7 PMID18543320 show ga Clara cells are nonciliated secretory cells lining the respiratory epithelium and are easily identified by the expression of Clara cell secretory protein (CCSP). To investigate molecular mechanism(s) regulating Clara cell function in the lungs, Cre recombinase was inserted into exon 1 of the CCSP, generating two novel mouse models, CCSP(Cre-Neo) and CCSP(Cre). These two models differ only by the inclusion of the neomycin resistance gene. These mice were bred to the R26R reporter mouse to investigate the tissue and cell specificity of Cre-mediated recombination. The efficiency of Cre recombination in the CCSP(Cre) mouse model was higher than in the CCSP(Cre-Neo) mouse model. Recombination was detected at D 4.5 in CCSP(Cre-Neo)/R26R mice and at D 0.5 in CCSP(Cre)/R26R mice. The CCSP(Cre-Neo) and CCSP(Cre) mouse models provide valuable tools for the ablation of genes in the postnatal mouse Clara cells. |*Recombination, Genetic [MESH] |Animals [MESH] |Crosses, Genetic [MESH] |Epithelial Cells/metabolism [MESH] |Exons [MESH] |Gene Targeting/methods [MESH] |Genes, Reporter [MESH] |Genetic Engineering [MESH] |Integrases/*genetics/metabolism [MESH] |Lung/metabolism [MESH] |Mice [MESH] |Mice, Transgenic [MESH] |Models, Genetic [MESH] |Respiratory Mucosa/*cytology/*metabolism [MESH]Cre-mediated recombination in mouse Clara cells (epmc).pdf DeepDyve Pubget Overpricing