Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1097/MNH.0000000000000121 http://scihub22266oqcxt.onion/10.1097/MNH.0000000000000121 C4466040!4466040 !25887899     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25887899 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Curr+Opin+Nephrol+Hypertens 2015 ; 24 (3 ): 224-30 Nephropedia Template TP {{tp|p=25887899 |t=2015. Counting glomeruli and podocytes: rationale and methodologies |pdf=|usr=}}{{25887899 }} gab.com Text Counting glomeruli and podocytes: rationale and methodologies JO: Curr Opin Nephrol Hypertens http://www.kidney.de/pget.php?&tw=1&pmid=25887899 #FOAvip PURPOSE OF REVIEW: There is currently much interest in the numbers of both glomeruli and podocytes. This interest stems from a greater understanding of the effects of suboptimal fetal events on nephron endowment, the associations between low nephron number and chronic cardiovascular and kidney disease in adults, and the emergence of the podocyte depletion hypothesis. RECENT FINDINGS: Obtaining accurate and precise estimates of glomerular and podocyte number has proven surprisingly difficult. When whole kidneys or large tissue samples are available, design-based stereological methods are considered gold standard because they are based on principles that negate systematic bias. However, these methods are often tedious and time consuming, and oftentimes inapplicable when dealing with small samples such as biopsies. Therefore, novel methods suitable for small tissue samples, and innovative approaches to facilitate high throughput measurements, such as MRI to estimate glomerular number and flow cytometry to estimate podocyte number, have recently been described. SUMMARY: This review describes current gold-standard methods for estimating glomerular and podocyte number, as well as methods developed in the past 3 years. We are now better placed than ever before to accurately and precisely estimate glomerular and podocyte number, and examine relationships between these measurements and kidney health and disease. Twit Text FOAVip Counting glomeruli and podocytes: rationale and methodologies ????Curr Opin Nephrol Hypertens http://www.kidney.de/pget.php?&tw=1&pmid=25887899 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25887899 #FOAvip English Wikipedia <ref>{{Cite pmid|25887899 }}</ref> Counting glomeruli and podocytes: rationale and methodologies #MMPMID25887899 Puelles VG ; Bertram JF Curr Opin Nephrol Hypertens 2015[May]; 24 (3 ): 224-30 PMID25887899 show ga PURPOSE OF REVIEW: There is currently much interest in the numbers of both glomeruli and podocytes. This interest stems from a greater understanding of the effects of suboptimal fetal events on nephron endowment, the associations between low nephron number and chronic cardiovascular and kidney disease in adults, and the emergence of the podocyte depletion hypothesis. RECENT FINDINGS: Obtaining accurate and precise estimates of glomerular and podocyte number has proven surprisingly difficult. When whole kidneys or large tissue samples are available, design-based stereological methods are considered gold standard because they are based on principles that negate systematic bias. However, these methods are often tedious and time consuming, and oftentimes inapplicable when dealing with small samples such as biopsies. Therefore, novel methods suitable for small tissue samples, and innovative approaches to facilitate high throughput measurements, such as MRI to estimate glomerular number and flow cytometry to estimate podocyte number, have recently been described. SUMMARY: This review describes current gold-standard methods for estimating glomerular and podocyte number, as well as methods developed in the past 3 years. We are now better placed than ever before to accurately and precisely estimate glomerular and podocyte number, and examine relationships between these measurements and kidney health and disease. |Animals [MESH] |Biopsy [MESH] |Cardiovascular Diseases/complications/pathology [MESH] |Humans [MESH] |Kidney Diseases/complications/*pathology [MESH] |Kidney Glomerulus/*pathology [MESH] |Kidney/*pathology [MESH] |Magnetic Resonance Imaging/methods [MESH]Counting glomeruli and podocytes: rationale and methodologies (epmc).pdf DeepDyve Pubget Overpricing