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2014 ; 5
(4
): e967602
Nephropedia Template TP
gab.com Text
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English Wikipedia
Contribution of transcription to animal early development
#MMPMID25483604
Wang J
; Davis RE
Transcription
2014[]; 5
(4
): e967602
PMID25483604
show ga
In mature gametes and during the oocyte-to-embryo transition, transcription is
generally silenced and gene expression is post-transcriptionally regulated.
However, we recently discovered that major transcription can occur immediately
after fertilization, prior to pronuclear fusion, and in the first cell division
of the oocyte-to-embryo transition in the nematode Ascaris suum. We postulate
that the balance between transcriptional and post-transcriptional regulation
during the oocyte-to-embryo transition may largely be determined by cell cycle
length and thus the time available for the genome to be transcribed.