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2018 ; 6
(2
): ä Nephropedia Template TP
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English Wikipedia
Consolidation and Exacerbation of COPD
#MMPMID29865214
Hurst JR
Med Sci (Basel)
2018[Jun]; 6
(2
): ä PMID29865214
show ga
20% of chronic obstructive pulmonary disease (COPD) patients admitted to hospital
because of an 'exacerbation' will have consolidation visible on a chest X-ray.
The presence of consolidation is associated with higher mortality. Imperfect
definitions of COPD exacerbation and pneumonia, and incomplete and imperfect
diagnostic tests, have resulted in a debate about whether these episodes are best
thought of as 'exacerbation with consolidation' or 'pneumonia in a person with
COPD'. With the current views that exacerbations are not all identical, and that
they can be 'phenotyped' to identify episodes with different prognosis and
treatment response, perhaps these episodes are best-considered a phenotype of
exacerbation. Whatever the terminology, the important clinical message is to
recognise that those with consolidation have higher mortality, and likely
different responses to treatment.