Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28553142
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28553142
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Cancer+Manag+Res
2017 ; 9
(ä): 167-178
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Considering renal risk while managing cancer
#MMPMID28553142
Shahinian VB
; Bahl A
; Niepel D
; Lorusso V
Cancer Manag Res
2017[]; 9
(ä): 167-178
PMID28553142
show ga
Renal function is an important consideration in the management of patients with
advanced cancer. There is a reciprocal relationship between cancer and the
kidney: chronic kidney disease can increase the risk of developing cancer, and
patients with cancer often experience renal impairment owing to age,
disease-related factors and nephrotoxic treatments. As therapies for cancer
continue to improve, patients are living longer with their disease, potentially
extending the period over which they are susceptible to long-term complications.
Furthermore, secondary symptoms, such as bone metastases or infections, may arise
that will require treatment. Certain treatments, including chemotherapy,
antibiotics and some bone-targeted agents, are nephrotoxic and may require dose
modifications or interruptions to prevent renal injury. Nephrologists should play
a key role in the identification and management of renal impairment in patients
with cancer. Furthermore, they may be able to provide advice on protecting the
kidneys in instances where nephrotoxic agents require dose reductions or
interruptions, and when novel therapies or combinations are used. Collaboration
between oncologists and nephrologists is important to optimal patient management.
This article reviews the relationship between cancer and kidney disease and
examines the treatments that may impact kidney function. Considerations for
monitoring renal function are also discussed.