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10.1016/j.febslet.2014.01.013 http://scihub22266oqcxt.onion/10.1016/j.febslet.2014.01.013 C3989427!3989427 !24457202     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24457202 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       FEBS+Lett 2014 ; 588 (8 ): 1212-20 Nephropedia Template TP {{tp|p=24457202 |t=2014. Connexins: mechanisms regulating protein levels and intercellular communication |pdf=|usr=}}{{24457202 }} gab.com Text Connexins: mechanisms regulating protein levels and intercellular communication JO: FEBS Lett http://www.kidney.de/pget.php?&tw=1&pmid=24457202 #FOAvip Intercellular communication can occur through gap junction channels, which are comprised of connexin proteins. Therefore, levels of connexins can directly correlate with gap junctional intercellular communication. Because gap junctions have a critical role in maintaining cellular homeostasis, the regulation of connexin protein levels is important. In the connexin life cycle, connexin protein levels can be modified through differential gene transcription or altered through trafficking and degradation mechanisms. More recently, significant attention has been directed to the pathways that cells utilize to increase or decrease connexin levels and thus indirectly, gap junctional communication. Here, we review the studies revealing the mechanisms that affect connexin protein levels and gap junctional intercellular communication. Twit Text FOAVip Connexins: mechanisms regulating protein levels and intercellular communication ????FEBS Lett http://www.kidney.de/pget.php?&tw=1&pmid=24457202 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24457202 #FOAvip English Wikipedia <ref>{{Cite pmid|24457202 }}</ref> Connexins: mechanisms regulating protein levels and intercellular communication #MMPMID24457202 Su V ; Lau AF FEBS Lett 2014[Apr]; 588 (8 ): 1212-20 PMID24457202 show ga Intercellular communication can occur through gap junction channels, which are comprised of connexin proteins. Therefore, levels of connexins can directly correlate with gap junctional intercellular communication. Because gap junctions have a critical role in maintaining cellular homeostasis, the regulation of connexin protein levels is important. In the connexin life cycle, connexin protein levels can be modified through differential gene transcription or altered through trafficking and degradation mechanisms. More recently, significant attention has been directed to the pathways that cells utilize to increase or decrease connexin levels and thus indirectly, gap junctional communication. Here, we review the studies revealing the mechanisms that affect connexin protein levels and gap junctional intercellular communication. |*Cell Communication [MESH] |*Proteolysis [MESH] |Animals [MESH] |Connexins/genetics/*metabolism [MESH] |Endocytosis [MESH] |Endoplasmic Reticulum-Associated Degradation [MESH] |Humans [MESH] |Intercellular Junctions/*metabolism [MESH] |Secretory Pathway [MESH]Connexins: mechanisms regulating protein levels and intercellular comm(epmc).pdf DeepDyve Pubget Overpricing