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10.1002/stem.2625 http://scihub22266oqcxt.onion/10.1002/stem.2625 C6047890!6047890 !28390147     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28390147 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28390147 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Stem+Cells 2017 ; 35 (6 ): 1461-1467 Nephropedia Template TP {{tp|p=28390147 |t=2017. Concise Review: Stem Cells in Osteoimmunology |pdf=|usr=}}{{28390147 }} gab.com Text Concise Review: Stem Cells in Osteoimmunology JO: Stem Cells http://www.kidney.de/pget.php?&tw=1&pmid=28390147 #FOAvip Bone remodeling is a lifelong process in which mature bone tissue is removed from the skeleton by bone resorption and is replenished by new during ossification or bone formation. The remodeling cycle requires both the differentiation and activation of two cell types with opposing functions; the osteoclast, which orchestrates bone resorption, and the osteoblast, which orchestrates bone formation. The differentiation of these cells from their respective precursors is a process which has been overshadowed by enigma, particularly because the precise osteoclast precursor has not been identified and because the identification of skeletal stem cells, which give rise to osteoblasts, is very recent. Latest advances in the area of stem cell biology have enabled us to gain a better understanding of how these differentiation processes occur in physiological and pathological conditions. In this review we postulate that modulation of stem cells during inflammatory conditions is a necessary prerequisite of bone remodeling and therefore an essential new component to the field of osteoimmunology. In this context, we highlight the role of transcription factor nuclear factor of activated T cells cytoplasmic 1 (NFATc1), because it directly links inflammation with differentiation of osteoclasts and osteoblasts. Stem Cells 2017;35:1461-1467. Twit Text FOAVip Concise Review: Stem Cells in Osteoimmunology ????Stem Cells http://www.kidney.de/pget.php?&tw=1&pmid=28390147 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28390147 #FOAvip English Wikipedia <ref>{{Cite pmid|28390147 }}</ref> Concise Review: Stem Cells in Osteoimmunology #MMPMID28390147 Fierro FA ; Nolta JA ; Adamopoulos IE Stem Cells 2017[Jun]; 35 (6 ): 1461-1467 PMID28390147 show ga Bone remodeling is a lifelong process in which mature bone tissue is removed from the skeleton by bone resorption and is replenished by new during ossification or bone formation. The remodeling cycle requires both the differentiation and activation of two cell types with opposing functions; the osteoclast, which orchestrates bone resorption, and the osteoblast, which orchestrates bone formation. The differentiation of these cells from their respective precursors is a process which has been overshadowed by enigma, particularly because the precise osteoclast precursor has not been identified and because the identification of skeletal stem cells, which give rise to osteoblasts, is very recent. Latest advances in the area of stem cell biology have enabled us to gain a better understanding of how these differentiation processes occur in physiological and pathological conditions. In this review we postulate that modulation of stem cells during inflammatory conditions is a necessary prerequisite of bone remodeling and therefore an essential new component to the field of osteoimmunology. In this context, we highlight the role of transcription factor nuclear factor of activated T cells cytoplasmic 1 (NFATc1), because it directly links inflammation with differentiation of osteoclasts and osteoblasts. Stem Cells 2017;35:1461-1467. |Animals [MESH] |Bone Resorption [MESH] |Bone and Bones/*cytology/*immunology [MESH] |Humans [MESH] |Models, Biological [MESH] |Osteoclasts/cytology [MESH] |Osteogenesis [MESH]Concise Review: Stem Cells in Osteoimmunology (epmc).pdf DeepDyve Pubget Overpricing