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10.1016/j.tig.2015.02.001 http://scihub22266oqcxt.onion/10.1016/j.tig.2015.02.001 C4380537!4380537 !25733351     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25733351 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25733351 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Trends+Genet 2015 ; 31 (4 ): 208-14 Nephropedia Template TP {{tp|p=25733351 |t=2015. Concepts in solid tumor evolution |pdf=|usr=}}{{25733351 }} gab.com Text Concepts in solid tumor evolution JO: Trends Genet http://www.kidney.de/pget.php?&tw=1&pmid=25733351 #FOAvip Evolutionary mechanisms in cancer progression give tumors their individuality. Cancer evolution is different from organismal evolution, however, and we discuss where concepts from evolutionary genetics are useful or limited in facilitating an understanding of cancer. Based on these concepts we construct and apply the simplest plausible model of tumor growth and progression. Simulations using this simple model illustrate the importance of stochastic events early in tumorigenesis, highlight the dominance of exponential growth over linear growth and differentiation, and explain the clonal substructure of tumors. Twit Text FOAVip Concepts in solid tumor evolution ????Trends Genet http://www.kidney.de/pget.php?&tw=1&pmid=25733351 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25733351 #FOAvip English Wikipedia <ref>{{Cite pmid|25733351 }}</ref> Concepts in solid tumor evolution #MMPMID25733351 Sidow A ; Spies N Trends Genet 2015[Apr]; 31 (4 ): 208-14 PMID25733351 show ga Evolutionary mechanisms in cancer progression give tumors their individuality. Cancer evolution is different from organismal evolution, however, and we discuss where concepts from evolutionary genetics are useful or limited in facilitating an understanding of cancer. Based on these concepts we construct and apply the simplest plausible model of tumor growth and progression. Simulations using this simple model illustrate the importance of stochastic events early in tumorigenesis, highlight the dominance of exponential growth over linear growth and differentiation, and explain the clonal substructure of tumors. |Animals [MESH] |Cell Differentiation [MESH] |Disease Progression [MESH] |Genetic Heterogeneity [MESH] |Humans [MESH] |Models, Biological [MESH] |Mutation [MESH]Concepts in solid tumor evolution (epmc).pdf DeepDyve Pubget Overpricing