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2015 ; 8
(4
): 44-7
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Comprehensive Tuberculosis Testing for the Dermatologist
#MMPMID26060517
Armstrong F
; Jordan L
J Clin Aesthet Dermatol
2015[Apr]; 8
(4
): 44-7
PMID26060517
show ga
Tuberculosis remains a noteworthy disease worldwide, rendering detection of
latent tuberculosis of great importance. As healthcare workers, dermatologists
should be aware of the available testing options and how they compare. In
general, the tuberculin skin test has been around longer and, thus, there have
been more studies performed on its sensitivity and specificity compared to
interferon gamma release assays, which are newer to the market. The tuberculin
skin test requires more office visits, takes longer to obtain results, is subject
to healthcare worker bias, and can cause a booster phenomenon; whereas,
interferon gamma release assays have a higher cost and less data available on
their use in children under five years old. Both the tuberculin skin test and
interferon gamma release assays fail to differentiate between recent and remote
infections, have a low predictive value for active tuberculosis, and a lower
sensitivity in people living with human immunodeficiency virus/acquired
immunodeficiency syndrome.