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2017 ; 114
(18
): 321-327
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Complication Rates in Colonoscopy Screening for Cancer
#MMPMID28587708
Zwink N
; Holleczek B
; Stegmaier C
; Hoffmeister M
; Brenner H
Dtsch Arztebl Int
2017[May]; 114
(18
): 321-327
PMID28587708
show ga
BACKGROUND: Screening colonoscopy has been offered in Germany since 2002.
Complications during colonoscopy were reported to be rare, but data on potential
complications after colonoscopy are sparse. We aimed to comprehensively assess
the frequency of complications arising during or within four weeks of screening
colonoscopy. METHODS: Residents of the German federal state of Saarland without a
history of colorectal cancer and without previous polypectomy who underwent a
screening colonoscopy between 2010 and 2013 were included. A follow-up was
conducted three months after the screening colonoscopy, including participant
questionnaires and subsequent validation of self-reported complications arising
during or within four weeks of screening colonoscopy, by reviewing colonoscopy
records and contacting the treating physicians. A comprehensive mortality
follow-up was conducted for non-responders. RESULTS: We recruited a total of 5527
participants from 26 practices (median age 61 years, 52% women). 5252 (95%) fully
completed the questionnaire on complications and met the inclusion criteria for
analysis. Among these participants, 16 cases of physician-confirmed bleeding
(0.30%) and four cases of physician-confirmed perforation (0.08%) occurred during
or within four weeks of colonoscopy. According to consistent reports from
patients and physicians, bleeding and perforation led to hospitalization in 5
(0.095%) and 2 (0.04%) cases, respectively. Three participants died within three
months of colo - noscopy. In none of these cases was the cause of death related
to colonoscopy. CONCLUSION: We found the risk of complications of screening
colonoscopy to be low, even when taking into account a potential delay of up to
four weeks.