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10.1016/j.coi.2014.02.010 http://scihub22266oqcxt.onion/10.1016/j.coi.2014.02.010 C4037377!4037377 !24681449     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=24681449 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24681449 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Curr+Opin+Immunol 2014 ; 28 (ä): 90-6 Nephropedia Template TP {{tp|p=24681449 |t=2014. Clonal and cellular dynamics in germinal centers |pdf=|usr=}}{{24681449 }} gab.com Text Clonal and cellular dynamics in germinal centers JO: Curr Opin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=24681449 #FOAvip Germinal centers (GCs) are the site of antibody affinity maturation, a process that involves complex clonal and cellular dynamics. Selection of B cells bearing higher-affinity immunoglobulins proceeds via a stereotyped pattern whereby B cells migrate cyclically between the GC's two anatomical compartments. This process occurs in a timeframe that is well suited to analysis by intravital microscopy, and much has been learned in recent years by use of these techniques. On a longer time scale, the diversity of B cell clones and variants within individual GCs is also thought to change as affinity maturation progresses; however, our understanding of clonal dynamics in individual GCs is limited. We discuss recent progress in the elucidation of clonal and cellular dynamics patterns. Twit Text FOAVip Clonal and cellular dynamics in germinal centers ????Curr Opin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=24681449 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24681449 #FOAvip English Wikipedia <ref>{{Cite pmid|24681449 }}</ref> Clonal and cellular dynamics in germinal centers #MMPMID24681449 Victora GD ; Mesin L Curr Opin Immunol 2014[Jun]; 28 (ä): 90-6 PMID24681449 show ga Germinal centers (GCs) are the site of antibody affinity maturation, a process that involves complex clonal and cellular dynamics. Selection of B cells bearing higher-affinity immunoglobulins proceeds via a stereotyped pattern whereby B cells migrate cyclically between the GC's two anatomical compartments. This process occurs in a timeframe that is well suited to analysis by intravital microscopy, and much has been learned in recent years by use of these techniques. On a longer time scale, the diversity of B cell clones and variants within individual GCs is also thought to change as affinity maturation progresses; however, our understanding of clonal dynamics in individual GCs is limited. We discuss recent progress in the elucidation of clonal and cellular dynamics patterns. |Animals [MESH] |B-Lymphocytes/immunology [MESH] |Cell Differentiation [MESH] |Germinal Center/cytology/*immunology [MESH] |Humans [MESH] |Immunoglobulins/immunology [MESH]Clonal and cellular dynamics in germinal centers (epmc).pdf DeepDyve Pubget Overpricing