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10.1111/bcp.12305 http://scihub22266oqcxt.onion/10.1111/bcp.12305 C4345947!4345947 !24325152     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24325152 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Br+J+Clin+Pharmacol 2015 ; 79 (3 ): 357-69 Nephropedia Template TP {{tp|p=24325152 |t=2015. Clinical trials in children |pdf=|usr=}}{{24325152 }} gab.com Text Clinical trials in children JO: Br J Clin Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=24325152 #FOAvip Safety and efficacy data on many medicines used in children are surprisingly scarce. As a result children are sometimes given ineffective medicines or medicines with unknown harmful side effects. Better and more relevant clinical trials in children are needed to increase our knowledge of the effects of medicines and to prevent the delayed or non-use of beneficial therapies. Clinical trials provide reliable evidence of treatment effects by rigorous controlled testing of interventions on human subjects. Paediatric trials are more challenging to conduct than trials in adults because of the paucity of funding, uniqueness of children and particular ethical concerns. Although current regulations and initiatives are improving the scope, quantity and quality of trials in children, there are still deficiencies that need to be addressed to accelerate radically equitable access to evidence-based therapies in children. Twit Text FOAVip Clinical trials in children ????Br J Clin Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=24325152 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24325152 #FOAvip English Wikipedia <ref>{{Cite pmid|24325152 }}</ref> Clinical trials in children #MMPMID24325152 Joseph PD ; Craig JC ; Caldwell PH Br J Clin Pharmacol 2015[Mar]; 79 (3 ): 357-69 PMID24325152 show ga Safety and efficacy data on many medicines used in children are surprisingly scarce. As a result children are sometimes given ineffective medicines or medicines with unknown harmful side effects. Better and more relevant clinical trials in children are needed to increase our knowledge of the effects of medicines and to prevent the delayed or non-use of beneficial therapies. Clinical trials provide reliable evidence of treatment effects by rigorous controlled testing of interventions on human subjects. Paediatric trials are more challenging to conduct than trials in adults because of the paucity of funding, uniqueness of children and particular ethical concerns. Although current regulations and initiatives are improving the scope, quantity and quality of trials in children, there are still deficiencies that need to be addressed to accelerate radically equitable access to evidence-based therapies in children. |*Clinical Trials as Topic/ethics/methods [MESH] |*Pediatrics/ethics/methods [MESH] |Child [MESH] |Drug Evaluation/ethics [MESH] |Drugs, Investigational/adverse effects/pharmacokinetics/therapeutic use [MESH] |Ethics, Medical [MESH] |Humans [MESH]Clinical trials in children (epmc).pdf DeepDyve Pubget Overpricing