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10.2147/OTT.S149786 http://scihub22266oqcxt.onion/10.2147/OTT.S149786 C5694205!5694205 !29180877     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29180877 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Onco+Targets+Ther 2017 ; 10 (ä): 5439-5443 Nephropedia Template TP {{tp|p=29180877 |t=2017. Clinical significance of CMTM4 expression in hepatocellular carcinoma |pdf=|usr=}}{{29180877 }} gab.com Text Clinical significance of CMTM4 expression in hepatocellular carcinoma JO: Onco Targets Ther http://www.kidney.de/pget.php?&tw=1&pmid=29180877 #FOAvip CMTM4 is the most conserved member of chemokine-like factor (CKLF)-like MARVEL transmembrane domain-containing (CMTM) family on chromosome 16q22.1, a locus that harbors a number of tumor-suppressor genes. In previous studies, CMTM4 was reported to be downregulated and exhibited tumor-suppressor activities by regulating cell growth and cell cycle in clear cell renal cell carcinoma. However, its roles in tumorigenesis of hepatocellular carcinoma (HCC) remain poorly studied. This study first investigated the expression of CMTM4 in HCC, and then examined the association between the expression of CMTM4 with the clinicopathological features and prognosis of HCC patients. It was found that CMTM4 was downregulated in HCC tissues, compared with matched adjacent nontumor tissues, as detected by immunohistochemistry. In addition, Kaplan-Meier survival analysis showed that the negative expression of CMTM4 was associated with decreased overall survival rates in patients with HCC. The results of this study suggest CMTM4 plays a role as a tumor suppressor in HCC and CMTM4 negative expression is a risk factor for poor prognosis of HCC. Twit Text FOAVip Clinical significance of CMTM4 expression in hepatocellular carcinoma ????Onco Targets Ther http://www.kidney.de/pget.php?&tw=1&pmid=29180877 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29180877 #FOAvip English Wikipedia <ref>{{Cite pmid|29180877 }}</ref> Clinical significance of CMTM4 expression in hepatocellular carcinoma #MMPMID29180877 Bei C ; Zhang Y ; Wei R ; Zhu X ; Wang Z ; Zeng W ; Chen Q ; Tan S Onco Targets Ther 2017[]; 10 (ä): 5439-5443 PMID29180877 show ga CMTM4 is the most conserved member of chemokine-like factor (CKLF)-like MARVEL transmembrane domain-containing (CMTM) family on chromosome 16q22.1, a locus that harbors a number of tumor-suppressor genes. In previous studies, CMTM4 was reported to be downregulated and exhibited tumor-suppressor activities by regulating cell growth and cell cycle in clear cell renal cell carcinoma. However, its roles in tumorigenesis of hepatocellular carcinoma (HCC) remain poorly studied. This study first investigated the expression of CMTM4 in HCC, and then examined the association between the expression of CMTM4 with the clinicopathological features and prognosis of HCC patients. It was found that CMTM4 was downregulated in HCC tissues, compared with matched adjacent nontumor tissues, as detected by immunohistochemistry. In addition, Kaplan-Meier survival analysis showed that the negative expression of CMTM4 was associated with decreased overall survival rates in patients with HCC. The results of this study suggest CMTM4 plays a role as a tumor suppressor in HCC and CMTM4 negative expression is a risk factor for poor prognosis of HCC. äClinical significance of CMTM4 expression in hepatocellular carcinoma (epmc).pdf DeepDyve Pubget Overpricing