Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28378259
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Clinical laser treatment of toenail onychomycoses
#MMPMID28378259
Zalacain A
; Merlos A
; Planell E
; Cantadori EG
; Vinuesa T
; Viñas M
Lasers Med Sci
2018[May]; 33
(4
): 927-933
PMID28378259
show ga
Onychomycoses are fungal infections of the fingernails or toenails having a
prevalence of 3% among adults and accounts for 50% of nail infections. It is
caused by dermatophytes, non-dermatophyte filamentous fungi, and yeasts.
Compressions and microtraumas significantly contribute to onychomycosis. Laser
and photodynamic therapies are being proposed to treat onychomycosis. Laser light
(1064 nm) was used to treat onychomycosis in 156 affected toenails. Patients were
clinically followed up for 9 months after treatment. Microbiological detection of
fungal presence in lesions was accomplished. A total of 116 samples allowed the
isolation of at least a fungus. Most of nails were affected in more than two
thirds surface (some of them in the full surface). In 85% of cases, after 18
months of the onset of treatment, culture turned negative. After 3 months months,
only five patients were completely symptom-free with negative culture. In 25
patients, only after 6 months, the absence of symptoms was achieved and the
cultures negativized; in 29 patients, 9 months were required. No noticeable
adverse effects were reported. This study reinforces previous works suggesting
the applicability of laser therapies to treat toenail onychomycosis.
free
free
free
