Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=24890835
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24890835
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Cold+Spring+Harb+Perspect+Med
2014 ; 4
(6
): ä Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Clinical characteristics and current treatment of glaucoma
#MMPMID24890835
Cohen LP
; Pasquale LR
Cold Spring Harb Perspect Med
2014[Jun]; 4
(6
): ä PMID24890835
show ga
Glaucoma is a neurodegenerative disorder in which degenerating retinal ganglion
cells (RGC) produce significant visual disability. Clinically, glaucoma refers to
an array of conditions associated with variably elevated intraocular pressure
(IOP) that contributes to RGC loss via mechanical stress, vascular abnormalities,
and other mechanisms, such as immune phenomena. The clinical diagnosis of
glaucoma requires assessment of the ocular anterior segment with slit lamp
biomicroscopy, which allows the clinician to recognize signs of conditions that
can produce elevated IOP. After measurement of IOP, a specialized prismatic lens
called a gonioscope is used to determine whether the angle is physically open or
closed. The structural manifestation of RGC loss is optic nerve head atrophy and
excavation of the neuroretinal rim tissue. Treatment is guided by addressing
secondary causes for elevated IOP (such as inflammation, infection, and ischemia)
whenever possible. Subsequently, a variety of medical, laser, and surgical
options are used to achieve a target IOP.