Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\32510106
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Nutr+Health+Aging
2020 ; 24
(6
): 560-562
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Clinical Presentation of COVID19 in Dementia Patients
#MMPMID32510106
Bianchetti A
; Rozzini R
; Guerini F
; Boffelli S
; Ranieri P
; Minelli G
; Bianchetti L
; Trabucchi M
J Nutr Health Aging
2020[]; 24
(6
): 560-562
PMID32510106
show ga
OBJECTIVE: No studies analyzing the role of dementia as a risk factor for
mortality in patients affected by COVID-19. We assessed the prevalence, clinical
presentation and outcomes of dementia among subjects hospitalized for COVID19
infection. DESIGN: Retrospective study. SETTING: COVID wards in Acute Hospital in
Brescia province, Northern Italy. PARTICIPANTS: We used data from 627 subjects
admitted to Acute Medical wards with COVID 19 pneumonia. MEASUREMENTS: Clinical
records of each patients admitted to the hospital with a diagnosis of COVID19
infection were retrospectively analyzed. Diagnosis of dementia, modalities of
onset of the COVID-19 infection, symptoms of presentation at the hospital and
outcomes were recorded. RESULTS: Dementia was diagnosed in 82 patients (13.1%).
The mortality rate was 62.2% (51/82) among patients affected by dementia compared
to 26.2% (143/545) in subjects without dementia (p<0.001, Chi-Squared test). In a
logistic regression model age, and the diagnosis of dementia resulted
independently associated with a higher mortality, and patients diagnosed with
dementia presented an OR of 1.84 (95% CI: 1.09-3.13, p<0.05). Among patients
diagnosed with dementia the most frequent symptoms of onset were delirium,
especially in the hypoactive form, and worsening of the functional status.
CONCLUSION: The diagnosis of dementia, especially in the most advanced stages,
represents an important risk factor for mortality in COVID-19 patients. The
clinical presentation of COVID-19 in subjects with dementia is atypical, reducing
early recognition of symptoms and hospitalization.
free
free
free
